Evidence-Based Nutrient Recommendations
Evidence-Based Nutrient Recommendations

Omega-3s and Depression

Published

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We added a study to the depression section of the omega 3s research page:

A 2019 meta-analysis and systematic review of 32 randomized controlled trials found little to no effect of increasing EPA and DHA on risk of depression symptoms (RR 1.01, CI 0.92-1.10). Studies had a median duration of 12 months with a median dose of 0.95 grams per day (ranging from 0.4 to 3.4 grams per day). One study addressed omega-3s and anxiety and found little to no effect. The researchers recommend against taking omega-3 supplements for reducing depression and anxiety risk.

References

Deane KHO, Jimoh OF, Biswas P, et al. Omega-3 and polyunsaturated fat for prevention of depression and anxiety symptoms: systematic review and meta-analysis of randomised trials [published online ahead of print, 2019 Oct 24]. Br J Psychiatry. 2019;1‐8.

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  • If you have a question about whether it's okay to cut supplements in half or combine supplements to achieve the dose we recommend, the answer is “Yes.” Be aware that nutrient recommendations are only estimates—it's not necessary to consume the exact amount we recommend every single day.
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